Semax
Neurotropic Heptapeptide
Dosage
10mg
Unit Size
1 Vial
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10mg
$80.00
17 in stock
What is Semax?
Semax is a synthetic heptapeptide derived from the ACTH 4-10 fragment, originally developed in Russia for cognitive enhancement and neuroprotection. It has been extensively studied for its effects on Brain-Derived Neurotrophic Factor (BDNF) — the key protein responsible for neuronal growth and synaptic plasticity. Semax is notable for its ability to cross the blood-brain barrier effectively and its broad cognitive and neuroprotective research profile.
7 aa
Amino Acid Chain
BDNF
Primary Target
BBB+
Blood-Brain Penetration
Key Benefits
BDNF Upregulation
Stimulates BDNF production in the hippocampus and cortex, promoting neuronal survival and new synapse formation.
Focus & Mental Clarity
Studied for enhanced focus, information processing speed, and mental clarity in cognitive research.
Memory & Learning
May improve learning retention and memory consolidation through hippocampal BDNF elevation and synaptic strengthening.
Neuroprotection
Demonstrated neuroprotective effects in stroke and brain injury models, reducing neuronal damage and accelerating recovery.
Anxiety & Stress Reduction
Investigated for reduction of anxiety markers and modulation of the stress response through enkephalin metabolism.
Neurotransmitter Modulation
Influences dopaminergic and serotonergic systems, contributing to mood stability and motivational research applications.
How It Works
BDNF Synthesis Stimulation
Semax upregulates the expression of BDNF in the hippocampus and cerebral cortex, the brain regions most critical for memory and learning.
Enkephalin Metabolism Modulation
It inhibits enkephalin-degrading enzymes, increasing levels of endogenous opioid peptides that regulate pain, mood, and stress responses.
Dopamine & Serotonin Pathway Activation
Semax modulates dopaminergic and serotonergic neurotransmission, contributing to its cognitive-enhancing and anxiolytic research profile.
Synaptic Plasticity Enhancement
Elevated BDNF supports long-term potentiation (LTP) — the cellular mechanism underlying learning, memory formation, and cognitive resilience.
Common Protocol (Research Reference)
300–600 mcg
Dose per session
1–2×/day
Frequency (intranasal)
2–4 wks
Typical cycle length
Research Use Notice
Semax is a research peptide not approved by the FDA for human use. This information is for educational purposes only. Always consult a qualified healthcare professional before considering any peptide protocol.