KPV
Anti-Inflammatory Tripeptide
Dosage
10mg
Unit Size
1 Vial
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10mg
$65.00
99 in stock
What is KPV?
KPV (Lysine-Proline-Valine) is a potent tripeptide derived from alpha-melanocyte-stimulating hormone (α-MSH) that exhibits powerful anti-inflammatory and healing properties. As the shortest active sequence of α-MSH, KPV delivers targeted anti-inflammatory action without the pigmentary effects of the parent molecule, making it one of the most studied peptides in inflammatory and mucosal healing research.
3 aa
Amino Acid Chain
α-MSH
Source Sequence
Mucosal
Primary Target
Key Benefits
Powerful Anti-Inflammatory
Suppresses inflammatory cytokine production and NF-κB signaling across multiple tissue types.
Wound Healing
Accelerates dermal and mucosal wound repair through enhanced epithelial regeneration.
Gut Healing
Studied for reducing intestinal inflammation and supporting healing in inflammatory bowel models.
Cytokine Modulation
Downregulates pro-inflammatory mediators including TNF-α, IL-1, and IL-6.
Respiratory Support
Research indicates protective effects in airway inflammation and allergic response models.
Safe Profile
Short sequence avoids melanocortin receptor activation linked to pigmentation, offering a refined safety profile.
How It Works
α-MSH Core Sequence
KPV corresponds to the C-terminal tripeptide of α-MSH, retaining the anti-inflammatory activity of the parent hormone.
NF-κB Inhibition
KPV inhibits NF-κB activation, the master regulator of inflammatory gene expression, reducing downstream cytokine release.
Cytokine Suppression
Directly reduces production of TNF-α, IL-1β, and IL-6, dampening the inflammatory cascade.
Epithelial Repair
Promotes migration and proliferation of epithelial cells, accelerating closure of mucosal and dermal wounds.
Common Protocol (Research Reference)
500 mcg–1 mg
Dose per injection
1–2×/day
Frequency
4–8 wks
Typical cycle length
Research Use Notice
KPV is a research peptide not approved by the FDA for human use. This information is for educational purposes only. Always consult a qualified healthcare professional before considering any peptide protocol.