ARA-290
Erythropoietin-Derived Peptide
Dosage
10mg
Unit Size
1 Vial
// Add to Cart
10mg
$70.00
99 in stock
What is ARA-290?
ARA-290 (Cibinetide) is an 11-amino-acid peptide derived from the helix B domain of erythropoietin (EPO). It is engineered to deliver the tissue-protective and anti-inflammatory benefits of EPO without stimulating red blood cell production. ARA-290 is studied for neuropathic pain, nerve regeneration, and inflammatory conditions, representing a refined approach to EPO-based repair signaling.
11 aa
Amino Acid Chain
EPO-Derived
Origin
CD131
Target Receptor
Key Benefits
Neuropathic Pain Relief
Studied for significant reduction of neuropathic pain in small fiber neuropathy and sarcoidosis models.
Nerve Regeneration
Promotes repair of damaged peripheral nerves and supports small nerve fiber regrowth.
Tissue Protection
Activates the EPO innate repair receptor to protect tissues from inflammatory and ischemic damage.
Anti-Inflammatory
Reduces inflammatory cytokine activity without the hematopoietic effects of full EPO.
No RBC Stimulation
Engineered to avoid erythropoiesis, allowing tissue-protective benefits without altering blood counts.
Cardio-Protective
Preclinical research suggests protective effects in cardiac ischemia and vascular injury models.
How It Works
Innate Repair Receptor
ARA-290 binds the CD131-based innate repair receptor (IRR), distinct from the EPO receptor that drives red blood cell production.
Anti-Apoptotic Signaling
Receptor activation triggers PI3K/Akt and STAT pathways that prevent apoptosis in stressed cells, preserving tissue viability.
Neuroregeneration
Supports Schwann cell function and axonal regrowth in peripheral nerves, addressing the root of neuropathic symptoms.
Inflammatory Modulation
Reduces NF-ÎșB-driven cytokine release, dampening the inflammation that underlies nerve damage and pain.
Common Protocol (Research Reference)
1â2 mg
Dose per injection
3Ă/week
Frequency
4â8 wks
Typical cycle length
Research Use Notice
ARA-290 is a research peptide not approved by the FDA for human use. This information is for educational purposes only. Always consult a qualified healthcare professional before considering any peptide protocol.